survey data procedures version 17 0 20 Search Results


excimer laser nidek ec-5000  (Nidek CO)
90
Nidek CO excimer laser nidek ec-5000
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
Excimer Laser Nidek Ec 5000, supplied by Nidek CO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
excimer laser nidek ec-5000 - by Bioz Stars, 2026-08
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interleukin 4  (Miltenyi Biotec)
93
Miltenyi Biotec interleukin 4
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
Interleukin 4, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
interleukin 4 - by Bioz Stars, 2026-08
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microwave decomposition system (mars 6  (CEM Corporation)
90
CEM Corporation microwave decomposition system (mars 6
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
Microwave Decomposition System (Mars 6, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
microwave decomposition system (mars 6 - by Bioz Stars, 2026-08
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microbanktm cryobeads  (Pro-Lab Diagnostics)
97
Pro-Lab Diagnostics microbanktm cryobeads
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
Microbanktm Cryobeads, supplied by Pro-Lab Diagnostics, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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microbanktm cryobeads - by Bioz Stars, 2026-08
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loose sieved black peat soil graberde  (Plantaflor Humus Verkaufs GmbH)
90
Plantaflor Humus Verkaufs GmbH loose sieved black peat soil graberde
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
Loose Sieved Black Peat Soil Graberde, supplied by Plantaflor Humus Verkaufs GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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x tdt buffer  (New England Biolabs)
98
New England Biolabs x tdt buffer
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
X Tdt Buffer, supplied by New England Biolabs, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 98 stars, based on 1 article reviews
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pi 17 0 20 4  (Avanti Polar)
93
Avanti Polar pi 17 0 20 4
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
Pi 17 0 20 4, supplied by Avanti Polar, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
pi 17 0 20 4 - by Bioz Stars, 2026-08
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anton paar rxa 170 analyzer  (Anton Paar)
90
Anton Paar anton paar rxa 170 analyzer
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
Anton Paar Rxa 170 Analyzer, supplied by Anton Paar, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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35-mm glass bottom dishes  (MatTek)
90
MatTek 35-mm glass bottom dishes
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
35 Mm Glass Bottom Dishes, supplied by MatTek, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
35-mm glass bottom dishes - by Bioz Stars, 2026-08
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170 whatman quartz fiber filter  (Danaher Inc)
99
Danaher Inc 170 whatman quartz fiber filter
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
170 Whatman Quartz Fiber Filter, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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c freundii  (ATCC)
90
ATCC c freundii
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
C Freundii, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1 2 diheptadecanoyl sn glycero 3 phosphocholine  (Avanti Polar)
95
Avanti Polar 1 2 diheptadecanoyl sn glycero 3 phosphocholine
Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an <t>excimer</t> laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.
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Image Search Results


Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an excimer laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.

Journal: Investigative Ophthalmology & Visual Science

Article Title: Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

doi: 10.1167/iovs.64.4.22

Figure Lengend Snippet: Wwtr1 deficient mice demonstrated impaired corneal endothelial wound healing after phototherapeutic keratectomy (PTK). An endothelial wound was created with an excimer laser (20 µm depth) in 6-month-old WT ( n = 6) and Wwtr1 +/− ( n = 6) mice. Optical coherence tomography (OCT) ( A, B ), slit lamp biomicroscopy ( C ), and in vivo confocal microscopy (IVCM) ( D ) were performed on post-injury days 1, 3, 5, 7, 10, and 14. Central corneal thickness (CCT) measured with OCT did not show statistical difference between the two genotypes ( B ), however, CCT reached its maximal thickness on post-injury days (PIDs) 7 to 10 and corneal edema was more marked on PID 10 in Wwtr1 +/− mice ( C ). IVCM revealed the regenerating course of injured endothelial cells throughout the study period ( D ). Following euthanasia on PID 14, endothelial wholemounts were stained with alizarin red ( E ), and endothelial cell density (ECD) was measured. ECD was significantly reduced in Wwtr1 +/− mice versus WT, suggesting impaired endothelial healing in Wwtr1 deficient mice. CCT was analyzed using a 2-way ANOVA, ECD was analyzed using a Mann-Whitney U test, * P < 0.05. OCT scale bars equivalent to 250 µm, IVCM and Alizarin red microscopy scale bars equivalent to 50 µm.

Article Snippet: Mice were sedated, then a drop of proparacaine was applied to anesthetize the cornea and an excimer laser injury (Nidek EC-5000 Excimer Laser, average fluence of 170 mK/cm 2 with an ablation zone diameter of 2 mm and depth of 20 μm) was performed.

Techniques: Tomography, In Vivo, Confocal Microscopy, Staining, MANN-WHITNEY, Microscopy